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Thyroglobulin antibodies should be measured by quantitative assays (RIA,
IRMA, ELISA) and are detected in about 60 to 70% of patients with autoimmune
thyreoditis and in 20 to 40% of Graves' patients. Because of a lower sensitivity
compared to TPO antibodies their value is limited and we do not advocate
their use as a routine primary tool in diagnosing autoimmune thyroid disease.
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