Recently Published Editions: No. 5 - 1999

Drug effects on thyroid function Jan R Stockigt, M.D., Melbourtne, Australia Introduction Alterations of TSH secretion Altered release of thyroid hormone from the gland Inhibition of 5' (outer ring) deiodination of T4 Discharge of tissue pools of thyroid hormone Altered circulating concentration of plasma binding proteins Competition for thyroid hormone binding to plasma proteins Impaired thyroxine absorption Enhanced thyroid hormone metabolism Drug interactions Agents that modify immune function Clinical issues with selected drugs Summary Author References