Figure 5:
Outcome of immunosuppressive treatment of Graves' ophthalmopathy as function of disease activity. The natural history of the activity and of the severity of the eye disease are depicted by two separate curves. Immunosuppression is given at half maximal disease severity: the response to treatment is negligible when given at zero disease activity (panel A) but substantial when applied at peak disease activity (panel B) (Wiersinga 1996).