1894
Thyroidinum siccatum
Introduction of desiccated sheep thyroid gland (powder, later
tablets) in Germany
1896
Thyroidin Merck (USA)
Offered in the price list published in Merck's 1896 Index
(New York)
1901
Antithyroidin Merck
Produced from the serum of thyrectomized rams (Moebius)
1912
Research on a standardized thyroid extract product
(Annual report Scientific Laboratory 1912)
1925
Evaluation of Kendall's Thyroxine
"Obviously thyroxine is not the only active thyroid
product"
1928
Novothyral
Introduction of water soluble standardized thyroid extract
(Axolotl)
1932
Thyroidea Opton
Introduction of protein-free degradation product of the
thyroid gland
1941
Thyroidin Merck
Standardized also with Axolotl method
1949
Methicil Merck
New antithyroid drug (Methyl-Thiouracil) in Germany
1968
Novothyral
Newly introduced as a T3/T4 combination in Germany
1973
Euthyrox
Mono T4 tablets introduced in Germany, later in many other
countries
1975
Jodid Merck
KI 100 mcg tablets (later 200 and 500 mcg) introduced in
Germany
1979
Kalium jodatum Compretten (100 mg KI)
Indicated for prevention of radioactive iodine
incorporporation in nuclear accidents
1985
Jodthyrox
T4/Iodide combination introduced in Germany for iodine
deficiency goiter
1990
Thyrozol
Introduction of thiamazole (methimazole) in 5 mg, 10 mg and
20 mg tablets
Since 1995
Introduction of Euthyrox on a global basis
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