Merck Thyroid History

 

1894

Thyroidinum siccatum 
Introduction of desiccated sheep thyroid gland (powder, later tablets) in Germany 

1896

Thyroidin Merck (USA) 
Offered in the price list published in Merck's 1896 Index (New York) 

1901

Antithyroidin Merck 
Produced from the serum of thyrectomized rams (Moebius) 

1912

Research on a standardized thyroid extract product 
(Annual report Scientific Laboratory 1912) 

1925

Evaluation of Kendall's Thyroxine 
"Obviously thyroxine is not the only active thyroid product" 

1928

Novothyral 
Introduction of water soluble standardized thyroid extract (Axolotl) 

1932

Thyroidea Opton 
Introduction of protein-free degradation product of the thyroid gland 

1941

Thyroidin Merck 
Standardized also with Axolotl method 

1949

Methicil Merck 
New antithyroid drug (Methyl-Thiouracil) in Germany 

1968

Novothyral 
Newly introduced as a T3/T4 combination in Germany 

1973

Euthyrox 
Mono T4 tablets introduced in Germany, later in many other countries 

1975

Jodid Merck 
KI 100 mcg tablets (later 200 and 500 mcg) introduced in Germany 

1979

Kalium jodatum Compretten (100 mg KI) 
Indicated for prevention of radioactive iodine incorporporation in nuclear accidents 

1985

Jodthyrox 
T4/Iodide combination introduced in Germany for iodine deficiency goiter 

1990

Thyrozol 
Introduction of thiamazole (methimazole) in 5 mg, 10 mg and 20 mg tablets 

Since 1995

Introduction of Euthyrox on a global basis

 

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